Improving mRNA’s stability and immunogenicity with an algorithm tool
Optimizing the structural stability of mRNA vaccines poses insurmountable computational challenges. An algorithm tool was developed by a research team in California to improve the structural stability of COVID-19 mRNA vaccine, leading to improved immune response.
The challenges of developing HIV vaccines
After 40 years of the HIV pandemic, we still don't have an HIV vaccine that works. Yet, COVID-19 vaccines were developed and tested effective in a year. Here are the reasons why.
RSV vaccines likely approved by FDA this year: a successful story of structural vaccinology
From fatal failure to today’s success in the phase III vaccine trial, the development of RSV vaccines tells a successful story of structural vaccinology.
Manage the discomfort following vaccination: would painkillers weaken the immune response?
Common over-the-counter pain relievers are available for managing the discomfort following vaccination. But it raises the concern that these drugs may reduce the efficacy of the vaccine.
A Brief History of Vaccines: an endless war between humans and pathogens
From smallpox vaccine in 1796 to mRNA vaccines in 2020. It is a long journey for scientists to design vaccines that are safe, effective, and cost-effective.